Diclofenac belongs to the anti-inflammatory series of drugs. Does not contain hormones or their analogues.
The medicine in the form of candles is used in the treatment of many diseases, including gynecological. These suppositories at the same time anesthetize, relieve edema, and fight tumors and infections.
On this page you will find all the information about Diclofenac: complete instructions for use for this drug, average prices in pharmacies, complete and incomplete analogues of the drug, as well as reviews of people who have already used Diclofenac candles. Want to leave your opinion? Please write in the comments.
NSAID, a derivative of phenylacetic acid.
Pharmacy sales terms
It is released on prescription.
How much do Diclofenac candles cost? The average price in pharmacies is 100 rubles.
Release form and composition
One suppository contains:
- active ingredient: diclofenac sodium 50 mg or 100 mg; excipients: cetyl alcohol, semisynthetic glycerides - enough to get a suppository weighing 2 g.
White or white with a yellowish tint suppositories are cylindrical. At the cut, the presence of an air and porous rod and a funnel-shaped recess is allowed.
Anti-inflammatory, analgesic, antipyretic. The mechanism of action is due to the suppression of prostaglandin biosynthesis by inhibiting cyclooxygenase, reducing the formation of kinins and other mediators of inflammation and pain, a stabilizing effect on lysosomal membranes.
In case of rheumatic diseases, it reduces swelling, hyperemia and pain in a state of rest and movement, morning stiffness and swelling of the joints, improving their functional ability. Relieves migraine attacks.
Indications for use
What helps candles Diclofenac? Here are the main indications for use:
- Ankylosing spondylarthrosis;
- Inflammation of the joints, muscles, ligaments;
- Arthritis (rheumatoid, infectious, gouty, traumatic);
- Myositis (aseptic inflammation of the skeletal muscles);
- Hernia or protrusion of intervertebral discs.
In combination with antispasmodics, suppositories can be used for hepatic or renal colic to relieve pain.
Additionally, rectal suppositories can be prescribed for other pathologies accompanied by pain and inflammation: the postoperative period, acute pain in the back or spine, tooth and headaches, infectious ENT diseases with a painful course.
Contraindications to the use of Diclofenac candles are:
- aggravation of peptic ulcer disease;
- bronchial asthma;
- patient age up to 16 years;
- hypersensitivity to the active ingredient or excipients;
- the period of coronary artery bypass surgery;
- mucous fissures;
- bleeding not related to menstruation;
- renal, cardiac or hepatic failure.
With extreme caution it is necessary to use the drug for the following diseases and conditions:
- liver disease;
- alcoholism, tendency to other bad habits (including smoking);
- heart ischemia;
- old age of patients;
- weakened body;
- insufficient body weight;
- stomach ulcer;
- Crohn's disease;
- low blood circulation;
- hypertonic disease;
- Helicobacter pylori infection;
- vascular disease.
It requires attention to the simultaneous use of Diclofenac with drugs:
- serotonin reuptake inhibitors;
- antiplatelet agents;
- nonsteroidal anti-inflammatory drugs.
Use during pregnancy and lactation
Not enough data on the safety of diclofenac in pregnant women. Therefore, the appointment in the I and II trimesters of pregnancy is possible only in cases where the expected benefit to the mother outweighs the potential risk to the fetus. Diclofenac (like other prostaglandin synthesis inhibitors) is contraindicated in the third trimester of pregnancy (suppression of uterine contractility and premature closure of the arterial duct in the fetus is possible).
Despite the fact that diclofenac is excreted in breast milk in small quantities, use during lactation (breastfeeding) is not recommended. If necessary, use during lactation breastfeeding should be discontinued.
Since diclofenac (like other NSAIDs) may have a negative effect on fertility, it is not recommended for use in women planning pregnancy.
Patients undergoing examination and treatment for infertility should be discontinued.
Instructions for use
The instructions for use indicate that Diclofenac suppositories are intended for rectal administration, as deeply as possible, after an act of defecation.
- Usually prescribed 50 mg twice a day or 100 mg once a day. The maximum dose for daily use is 150 mg. The duration of treatment is determined individually.
- For migraine: 100-150 mg for the first attacks.
Suppositories are administered whole, without cutting into pieces, because this can lead to impaired absorption.
Diclofenac in the form of candles smoothes the negative impact on the organs of the digestive system, kidneys, liver, but does not protect against all side effects typical of this group of drugs.
Unpleasant sensations appear in the intestines:
- Abdominal pain;
- Burning sensation at the site of the suppository;
- Constipation or diarrhea;
- Unpleasant taste in the mouth.
Side effects are enhanced with prolonged use of suppositories, overdose, combination with other nonsteroidal anti-inflammatory drugs, with individual intolerance to the components.
In case of overdose appear:
- high blood pressure;
- noise in ears;
- vomiting and nausea;
- pain in the abdomen.
Before you start using the drug, you should carefully read the instructions for it, there are several special instructions that should be considered:
- The possibility of using the drug for pregnant women in the I and II trimester of pregnancy is determined by the doctor, comparing the expected benefits to the mother and the potential risk to the fetus.
- In the case of long-term use of Diclofenac suppositories, laboratory monitoring of blood coagulation parameters, the functional activity of the kidneys and liver is required.
- The parallel use of drugs from the group of nonsteroidal anti-inflammatory drugs requires a reduction in the dosage of candles Diclofenac.
It is not recommended to perform work associated with an increased concentration of attention or speed of psychomotor reactions due to the possible development of side effects from the central nervous system.
- Reduces the effect of diuretics, against the background of potassium-saving diuretics increases the risk of hyperkalemia.
- When used together, it increases the plasma concentration of lithium, digoxin.
- The concentration of diclofenac in plasma decreases with simultaneous use of acetylsalicylic acid.
- While taking anticoagulants (including warfarin), antiplatelet (including acetylsalicylic acid, clopidogrel) and thrombolytic drugs (including increased risk of bleeding (chap grate).
- Reduces the effect of hypoglycemic, hypotensive and hypnotic drugs.
- When combined with other NSAIDs and glucocorticoid drugs (including prednisone) increases the likelihood of side effects (gastrointestinal bleeding).
- Combined use with paracetamol, cyclosporine and gold preparations increases the risk of nephrotoxic effects.
- Selective serotonin reuptake inhibitors (including citalopram, fluoxetine, paroxetine, sertraline) increase the risk of bleeding in the gastrointestinal tract.
- The simultaneous appointment with colchicine and corticotropin increases the risk of bleeding in the gastrointestinal tract.
- Drugs that block tubular secretion (including verapamil, nifedipine, diltiazem) increase the plasma concentration of diclofenac, thereby increasing its efficacy and toxicity. Antibacterial agents, quinolone derivatives increase the risk of seizures.
We picked up some reviews from people about Diclofenac candles:
- Marina. Used in the treatment of cystitis in combination with other drugs. Therapy lasted 10 days, successfully completed. There were side effects, but it’s hard to tell from which drugs. I use candles periodically, as soon as the cystitis makes itself felt.
- Veronica. I got an interesting situation. Appealed to the gynecologist with suspected inflammation. There was a delay of menstrual periods, characteristic of inflammation, aching pain in the abdomen, lower back. The doctor examined, said nothing like that. As a result, Diclofenac appointed candles to herself. Successfully treated for 5 days. On this my problem disappeared. There were discomfort in the abdomen, a chair was broken, a little sweating. Everything returned to normal after discontinuation of the drug for 3 days. Effective, effective tool. I am glad that it acts in several directions at once. Do not have to stuff yourself with different medicines.
- Ksyusha I like candles, only they help, because the pain is such that even hang yourself. I use them only during menstruation for a long time, they used to help better! Any medicine is harmful, but here you have to decide for yourself that it is better to endure pain or suffer from side effects!
According to the active substance and therapeutic effect similar to Diclofenac candles are drugs - Voltaren candles, Diklovit candles.
Before using analogues consult your doctor.
Storage conditions and shelf life
The drug is usable for three years from the date of issue printed on the package, after the expiration date of the drug is not stored and is not used as it is subject to disposal.
Diclofenac can be stored strictly at a temperature of 15 to 25 degrees Celsius, out of the reach of children. Storage should be protected from moisture and direct sunlight.